The biggest minivan from Honda received a new generation in 2010, badged as a 2011 model.
It was the fourth generation of the Odyssey journey and the premiere took place at the Chicago Auto Show. The features shown on the car convinced over 100.000 customers every year until the model change in 2017, in all four trim levels.

The 5.154 mm (202.9 in) long car had room for 7 people, two sliding doors and a big trunk, which could be increased by folding or removing two seat rows. The new infotainment system included a voice-controlled XM-NavTraffic system with on-board HDD.

New for the fifth generation of the Odyssey were also the headlights, which featured HID Xenon bulbs. In the rear, a power-activated tailgate was available as an option. For the upper trim levels, Honda installed 18” light-alloy wheels and an infotainment unit with a split-screen rear-seats DVD entertainment system. Also, a multi-zone climate control system was offered, but no AWD function for either variants.

Under the hood, there was the 3.5-liter gasoline V6 engine, borrowed and tuned for minivan use from the Honda Pilot SUV. It offers 255 hp and 339 Nm (250 lb.-ft) of torque. The only transmission offered was a 5-speed automatic, with front-wheel-drive. The Touring trim model was equipped with a 6-speed automatic transmission.